microRNAs in cancer management.
作者： Yi W Kong , David Ferland-McCollough , Thomas J Jackson , Martin Bushell , None
DOI: 10.1016/S1470-2045(12)70073-6
关键词: Bioinformatics 、 Mechanism (biology) 、 Computational biology 、 Gene expression 、 Regulation of gene expression 、 Gene 、 Small RNA 、 Malignancy 、 Biology 、 microRNA 、 Metastasis
摘要: Summary Since the identification of microRNAs (miRNAs) in 1993, and subsequent discovery their highly conserved nature 2000, amount research into function—particularly how they contribute to malignancy—has greatly increased. This class small RNA molecules control gene expression provide a previously unknown mechanism for protein synthesis. As such, it is unsurprising that miRNAs are now known play an essential part malignancy, functioning as tumour suppressors oncogenes. Review summarises present understanding operate at molecular level; dysregulation crucial formation, maintenance, metastasis; can be used biomarkers disease type grade; miRNA-based treatments could diverse types malignancies.
elsevier.com
sci-hub.se 参考文章(87)
Carl E Freter, Li-Qun Gu, Dali Zheng, Shadi Haddadin, Yong Wang, Michael X Wang, Michael C Perry, Plasma microRNAs as novel biomarkers for early detection of lung cancer. International Journal of Clinical and Experimental Pathology. ,vol. 4, pp. 575- 586 ,(2011)
Phong Trang, Jason F Wiggins, Christopher L Daige, Chris Cho, Michael Omotola, David Brown, Joanne B Weidhaas, Andreas G Bader, Frank J Slack, Systemic Delivery of Tumor Suppressor microRNA Mimics Using a Neutral Lipid Emulsion Inhibits Lung Tumors in Mice Molecular Therapy. ,vol. 19, pp. 1116- 1122 ,(2011) , 10.1038/MT.2011.48
Hiroshi Maeda, Jun Fang, Takao Inutsuka, Yasunori Kitamoto, Vascular permeability enhancement in solid tumor: various factors, mechanisms involved and its implications. International Immunopharmacology. ,vol. 3, pp. 319- 328 ,(2003) , 10.1016/S1567-5769(02)00271-0
Philip A. Gregory, Andrew G. Bert, Emily L. Paterson, Simon C. Barry, Anna Tsykin, Gelareh Farshid, Mathew A. Vadas, Yeesim Khew-Goodall, Gregory J. Goodall, The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 Nature Cell Biology. ,vol. 10, pp. 593- 601 ,(2008) , 10.1038/NCB1722
Kathryn A. O'Donnell, Erik A. Wentzel, Karen I. Zeller, Chi V. Dang, Joshua T. Mendell, c-Myc-regulated microRNAs modulate E2F1 expression. Nature. ,vol. 435, pp. 839- 843 ,(2005) , 10.1038/NATURE03677
Xingyong Wu, Hongjian Liu, Jianquan Liu, Kari N. Haley, Joseph A. Treadway, J Peter Larson, Nianfeng Ge, Frank Peale, Marcel P. Bruchez, Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots Nature Biotechnology. ,vol. 21, pp. 41- 46 ,(2003) , 10.1038/NBT764
Jaclyn A. Freudenberg, Qiang Wang, Makoto Katsumata, Jeffrey Drebin, Izumi Nagatomo, Mark I. Greene, The role of HER2 in early breast cancer metastasis and the origins of resistance to HER2-targeted therapies. Experimental and Molecular Pathology. ,vol. 87, pp. 1- 11 ,(2009) , 10.1016/J.YEXMP.2009.05.001
Takayuki Kogure, Wen-Lang Lin, Irene K. Yan, Chiara Braconi, Tushar Patel, Intercellular nanovesicle-mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth. Hepatology. ,vol. 54, pp. 1237- 1248 ,(2011) , 10.1002/HEP.24504
F Yu, H Deng, H Yao, Q Liu, F Su, E Song, Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells Oncogene. ,vol. 29, pp. 4194- 4204 ,(2010) , 10.1038/ONC.2010.167
A. Cimmino, G. A. Calin, M. Fabbri, M. V. Iorio, M. Ferracin, M. Shimizu, S. E. Wojcik, R. I. Aqeilan, S. Zupo, M. Dono, L. Rassenti, H. Alder, S. Volinia, C.-g. Liu, T. J. Kipps, M. Negrini, C. M. Croce, miR-15 and miR-16 induce apoptosis by targeting BCL2. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 102, pp. 13944- 13949 ,(2005) , 10.1073/PNAS.0506654102