Regulation of lung epithelial cell morphology by cAMP-dependent protein kinase type I isozyme.
作者： Stephanie E. Porter , Lori D. Dwyer-Nield , Alvin M. Malkinson
DOI: 10.1152/AJPLUNG.2001.280.6.L1282
关键词: Protein kinase A 、 Biology 、 Isozyme 、 Actin 、 Cell biology 、 Protein phosphorylation 、 Actin cytoskeleton 、 Cytoskeleton 、 Vinculin 、 Cell culture
摘要: Cell shape is mediated in part by the actin cytoskeleton and actin-binding protein vinculin. These proteins turn are regulated phosphorylation. We assessed contribution of cAM...
sci-hub.se 参考文章(44)
G. STANLEY MCKNIGHT, CHRISTOPHER H. CLEGG, MICHAEL D. UHLER, JOHN C. CHRIVIA, GARY G. CADD, LESLAY A. CORRELL, ANNE D. OTTEN, Analysis of the cAMP-Dependent Protein Kinase System Using Molecular Genetic Approaches Recent Progress in Hormone Research. ,vol. 44, pp. 307- 335 ,(1988) , 10.1016/B978-0-12-571144-9.50014-4
Marcos Malumbres, Angel Pellicer, RAS pathways to cell cycle control and cell transformation Frontiers in Bioscience. ,vol. 3, pp. d887- 912 ,(1998) , 10.2741/A331
Yoon S. Cho-Chung, Antisense oligonucleotide inhibition of serine/threonine kinases: an innovative approach to cancer treatment. Pharmacology & Therapeutics. ,vol. 82, pp. 437- 449 ,(1999) , 10.1016/S0163-7258(98)00043-6
Pierre P. Roger, Sylvia Reuse, Carine Maenhaut, Jacques E. Dumont, Multiple Facets of the Modulation of Growth by cAMP Vitamins and Hormones Series. ,vol. 51, pp. 59- 191 ,(1995) , 10.1016/S0083-6729(08)61038-9
C A Lange-Carter, T Fossli, T Jahnsen, A M Malkinson, Decreased expression of the type I isozyme of cAMP-dependent protein kinase in tumor cell lines of lung epithelial origin. Journal of Biological Chemistry. ,vol. 265, pp. 7814- 7818 ,(1990) , 10.1016/S0021-9258(19)39002-7
C E Turner, F M Pavalko, K Burridge, The role of phosphorylation and limited proteolytic cleavage of talin and vinculin in the disruption of focal adhesion integrity Journal of Biological Chemistry. ,vol. 264, pp. 11938- 11944 ,(1989) , 10.1016/S0021-9258(18)80157-0
Inhibition of intracellular cAMP-dependent protein kinase using mutant genes of the regulatory type I subunit. Journal of Biological Chemistry. ,vol. 262, pp. 13111- 13119 ,(1987) , 10.1016/S0021-9258(18)45175-7
C.A. Lange-Carter, A.M. Malkinson, Altered regulation of mRNA levels encoding the type I isozyme of cAMP-dependent protein kinase in neoplastic mouse lung epithelial cells. Journal of Biological Chemistry. ,vol. 266, pp. 22529- 22536 ,(1991) , 10.1016/S0021-9258(18)54604-4
M D Uhler, G S McKnight, Expression of cDNAs for two isoforms of the catalytic subunit of cAMP-dependent protein kinase. Journal of Biological Chemistry. ,vol. 262, pp. 15202- 15207 ,(1987) , 10.1016/S0021-9258(18)48158-6
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)