作者: C. J. Stankewich , Marc F. Swiontkowski , Allan F. Tencer , Duran N. Yetkinler , Robert D. Poser
关键词: Medicine 、 Femoral head 、 Fixation (histology) 、 Fracture fixation 、 Surgery 、 Femoral Neck Fractures 、 Femoral neck 、 Bone mineral 、 Nuclear medicine 、 Cancellous bone 、 Femur
摘要: The first goal of this study was to determine if augmentation with an injectable, in situ setting, calcium-phosphate cement that is capable being remodeled and designed mimic bone mineral significantly improved the strength stiffness fixation a cadaveric femoral neck fracture model. second greater increases were achieved as density specimen decreased. Sixteen pairs fresh human femora mean age 70.9 years (SD = 17.2 years) utilized. measured dual-energy x-ray absorptiometry. head impacted vertically shaft fixed 12 degrees adduction using materials testing machine create fully displaced fracture. Following fracture, 30% inferior comminution created each specimen. One randomly chosen femur from pair underwent anatomic reduction three cannulated cancellous screws, 7 mm diameter, inverted triangle configuration. contralateral same augmented cement. Specimens preconditioned followed by 1.000 cycles one body weight (611.6 N) at 0.5 Hz simulate single-limb stance loading. cycle observed be cement-augmented specimens compared unaugmented controls (p < 0.05). After cycling, loaded 10 mm/min until complete displacement surface failure occurred. failed 4,573 N 1,243 N); 0.01) than for (3,092 N, SD 1,258 N). relative improvement (augmented/control x 100%) not inversely correlated 0.25, R2 0.09), weakly volume injected 0.07, 0.22), related load control 0.001, 0.54). There 169.6% 77.5). These findings suggest provides initial beneficial fractures.