The application and impact of cryopreservation of early cleavage stage embryos in assisted reproduction.

作者: David H. Edgar , Janell Archer , Harold Bourne

DOI: 10.1080/14647270500054779

关键词: BlastomereAndrologyEmbryo cryopreservationEmbryoPregnancyIn vitro fertilisationPopulationBiologyEmbryo transferCryopreservation

摘要: The contribution of cryopreserved embryos to the overall outcomes achieved by a clinical assisted reproduction programme has increased in importance with trend towards reducing numbers fresh transferred following vitro fertilisation. Although cryopreservation appears fully preserve developmental potential early cleavage stage that survive intact, it results reduction when blastomere loss occurs during freezing and thawing. Overall, can be estimated approximately 30% for pregnancy population embryos. Both survival post-thaw resumption mitosis act as markers implantation frozen/thawed Application strict criteria transferring thawed may enhance apparent success rates, but also result some being discarded. role embryo minimising incidence mult...

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