Regulation of Cerebral Artery Smooth Muscle Membrane Potential by Ca2+‐Activated Cation Channels
作者： Albert L. Gonzales , Scott Earley
DOI: 10.1111/MICC.12023
关键词: T-type calcium channel 、 Cardiac action potential 、 Graded potential 、 Biophysics 、 Biology 、 Internal medicine 、 Depolarization 、 Ion channel 、 Membrane potential 、 Endocrinology 、 Smooth muscle contraction 、 Voltage-dependent calcium channel
摘要: Arterial tone is dependent on the depolarizing and hyperpolarizing currents regulating membrane potential governing influx of Ca2+ needed for smooth muscle contraction. Several ion channels have been proposed to contribute depolarization, but underlying molecular mechanisms are not fully understood. In this review, we will discuss historical physiological significance Ca2+-activated cation channel, TRPM4, in cerebral artery cells. As a member recently described transient receptor super family channels, TRPM4 possesses biophysical properties upstream cellular signaling regulatory pathways that establish it as major player depolarization.
sci-hub.se 参考文章(102)
Pierre Launay, Andrea Fleig, Anne-Laure Perraud, Andrew M. Scharenberg, Reinhold Penner, Jean-Pierre Kinet, TRPM4 Is a Ca2+-Activated Nonselective Cation Channel Mediating Cell Membrane Depolarization Cell. ,vol. 109, pp. 397- 407 ,(2002) , 10.1016/S0092-8674(02)00719-5
Mario J. Rebecchi, Srinivas N. Pentyala, Structure, Function, and Control of Phosphoinositide-Specific Phospholipase C Physiological Reviews. ,vol. 80, pp. 1291- 1335 ,(2000) , 10.1152/PHYSREV.2000.80.4.1291
Donald G. Welsh, Mark T. Nelson, Delrae M. Eckman, Joseph E. Brayden, Swelling‐activated cation channels mediate depolarization of rat cerebrovascular smooth muscle by hyposmolarity and intravascular pressure The Journal of Physiology. ,vol. 527, pp. 139- 148 ,(2000) , 10.1111/J.1469-7793.2000.T01-1-00139.X
C C Aickin, A F Brading, The effect of loop diuretics on Cl- transport in smooth muscle of the guinea-pig vas deferens and taenia from the caecum. The Journal of Physiology. ,vol. 421, pp. 33- 53 ,(1990) , 10.1113/JPHYSIOL.1990.SP017932
Rachael Crnich, Gregory C. Amberg, M. Dennis Leo, Albert L. Gonzales, Michael M. Tamkun, Jonathan H. Jaggar, Scott Earley, Vasoconstriction resulting from dynamic membrane trafficking of TRPM4 in vascular smooth muscle cells American Journal of Physiology-cell Physiology. ,vol. 299, ,(2010) , 10.1152/AJPCELL.00101.2010
Victor Matveev, Robert S. Zucker, Arthur Sherman, Facilitation through buffer saturation: constraints on endogenous buffering properties. Biophysical Journal. ,vol. 86, pp. 2691- 2709 ,(2004) , 10.1016/S0006-3495(04)74324-6
Ajay Dhaka, Veena Viswanath, Ardem Patapoutian, TRP ION CHANNELS AND TEMPERATURE SENSATION Annual Review of Neuroscience. ,vol. 29, pp. 135- 161 ,(2006) , 10.1146/ANNUREV.NEURO.29.051605.112958
Alexander Dietrich, Michael Mederos y Schnitzler, Maik Gollasch, Volkmar Gross, Ursula Storch, Galyna Dubrovska, Michael Obst, Eda Yildirim, Birgit Salanova, Hermann Kalwa, Kirill Essin, Olaf Pinkenburg, Friedrich C. Luft, Thomas Gudermann, Lutz Birnbaumer, Increased vascular smooth muscle contractility in TRPC6-/- mice. Molecular and Cellular Biology. ,vol. 25, pp. 6980- 6989 ,(2005) , 10.1128/MCB.25.16.6980-6989.2005
Annelies Janssens, Grzegorz Owsianik, Rudi Vennekens, Thomas Voets, Bernd Nilius, Frank Mahieu, Jean Prenen, The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate The EMBO Journal. ,vol. 25, pp. 467- 478 ,(2006) , 10.1038/SJ.EMBOJ.7600963
Bernd Nilius, Jean Prenen, Annelies Janssens, Thomas Voets, Guy Droogmans, Decavanadate modulates gating of TRPM4 cation channels. The Journal of Physiology. ,vol. 560, pp. 753- 765 ,(2004) , 10.1113/JPHYSIOL.2004.070839