Vasoconstriction resulting from dynamic membrane trafficking of TRPM4 in vascular smooth muscle cells

作者: Rachael Crnich , Gregory C. Amberg , M. Dennis Leo , Albert L. Gonzales , Michael M. Tamkun

DOI: 10.1152/AJPCELL.00101.2010

关键词: BiochemistryVasoconstrictionCellDepolarizationMembrane transportCell biologyProtein kinase CTransient receptor potential channelCerebral arteriesBiologyVascular smooth muscle

摘要: The melastatin (M) transient receptor potential (TRP) channel TRPM4 mediates pressure and protein kinase C (PKC)-induced smooth muscle cell depolarization vasoconstriction of cerebral arteries....

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