The role of pattern analysis and the ABCD rule of dermoscopy in the detection of histological atypia in melanocytic naevi

摘要: Background Clinical features of melanocytic naevi correlate poorly with the presence, histopathologically, architectural disorder and cytological atypia, making detection histological atypia by means macroscopic appearance unreliable.  Objectives The aim this study was to investigate diagnostic effectiveness dermoscopy in non-invasive naevi.  Methods Observers blinded for diagnosis classified a series 168 as common or atypical on basis their clinical dermoscopic profile. The performance both methods compared true (histopathological) assessed.  Results Dermoscopy using pattern analysis showed better results than examination without (diagnostic accuracy 45% vs. 28%). A statistically significant difference frequency parameters between found pigment network (39% 17%, P = 0·001) regression structures (13% 2%, P = 0·008). Dermoscopic features, which best predicted naevi, were (white scar-like areas peppering), irregular vascular grey–blue (positive predictive values 83%, 83% 73%, respectively). In contrast, no mean ABCD score found. rule (cut-off point 4·0 total score) not dissimilar that 30%).  Conclusions Dermoscopy enhances dermatologists prediction alone.