Spinal G-Protein-Gated K+ Channels Formed by GIRK1 and GIRK2 Subunits Modulate Thermal Nociception and Contribute to Morphine Analgesia

作者: Cheryl L Marker , Markus Stoffel , Kevin Wickman

DOI: 10.1523/JNEUROSCI.5251-03.2004

关键词: TertiapinChannel blockerG proteinMorphineInhibitory postsynaptic potentialOpioidNociceptionHyperalgesiaChemistryPharmacology

摘要: … Furthermore, GIRK1 knock-out and GIRK2 knock-out … -gated K + channel blocker tertiapin. We conclude that spinal G-protein-gated K + channels consisting primarily of GIRK1/GIRK2 …

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