Psychopathology, personality traits and social development of young first-degree relatives of patients with schizophrenia
作者： Stephen J. Glatt , William S. Stone , Stephen V. Faraone , Larry J. Seidman , Ming T. Tsuang
DOI: 10.1192/BJP.BP.105.016998
关键词: First-degree relatives 、 Psychopathology 、 Anhedonia 、 Schizophrenia 、 Personality 、 Reward dependence 、 Psychology 、 Developmental psychology 、 Longitudinal study 、 Personality development
摘要: Background Evaluation of individuals at high genetic risk schizophrenia is a powerful method for identifying precursors the illness. Aims To identify aspects personality, psychopathology and social development that differentiate high-risk control individuals. Method Adolescent young-adult first-degree relatives ( n =35) people with or schizoaffective disorder group =55) were compared on 36 measures baseline longitudinal study. Measures differentiating participants related to four loading indices. Results High-risk older than 17 years showed more physical anhedonia, less positive involvement peers problems peers, siblings opposite gender. Older also cooperative, self-directed reward-dependent. Problems gender, as well reward dependence, linearly loading. Conclusions Alterations in personality traits are present individuals, may be markers liability toward illness.
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