Chronic haemorrhagic radiation proctitis: A review

作者: Vishnu Prasad Nelamangala Ramakrishnaiah , Srinivasan Krishnamachari

DOI: 10.4240/WJGS.V8.I7.483

关键词: Radiation proctitisProctitisStandard treatmentSurgeryRandomized controlled trialSystematic reviewRadiation therapyArgon plasma coagulationClinical trialMedicine

摘要: Chronic haemorrhagic radiation proctitis (CHRP) is a difficult problem faced by the patients following for pelvic malignancy. There no standard treatment this condition, but many methods of are available. The aim study was to review literature see whether there an improvement in available evidence comparison with previously published systematic reviews treating CHRP. PubMed/Medline database and Google Scholar search selectively searched. Studies, which treated rectal bleeding due chronic or CHRP, were included. Seventy studies finally selected out 14 randomized controlled clinical trials. Though these could not be compared, it seen that methodology studies. objective assessment symptoms, signs outcomes. But, still, only few looked into quality life To increase recruitment trials, national registry cases established late toxicity would facilitate further such Some conclusions reached based on 4% formalin should first line Formalin argon plasma coagulation (APC) equally effective, better severe disease. Refractory patients, responding APC, need referred hyperbaric oxygen therapy surgery. Radio-frequency ablation promising modality needs studied

参考文章(73)
Juan Ayerdi, Khaja Moinuddeen, Alice Loving, Jeffrey Wiseman, Narayan Deshmukh, Diverting loop colostomy for the treatment of refractory gastrointestinal bleeding secondary to radiation proctitis. Military Medicine. ,vol. 166, pp. 1091- 1093 ,(2001) , 10.1093/MILMED/166.12.1091
K. W. Eu, C. L. Tang, J. F. Lim, M. T. C. Wong, B. S. Ooi, K. S. Ho, Radiation proctitis: a decade's experience. Singapore Medical Journal. ,vol. 51, pp. 315- 319 ,(2010)
V. P. Nelamangala Ramakrishnaiah, T. D. Javali, K. Dharanipragada, K. S. Reddy, S. Krishnamachari, Formalin dab, the effective way of treating haemorrhagic radiation proctitis: a randomized trial from a tertiary care hospital in South India Colorectal Disease. ,vol. 14, pp. 876- 882 ,(2012) , 10.1111/J.1463-1318.2012.03008.X
M. R. Chruscielewska-Kiliszek, J. Regula, M. Polkowski, M. Rupinski, E. Kraszewska, J. Pachlewski, E. Czaczkowska-Kurek, E. Butruk, Sucralfate or placebo following argon plasma coagulation for chronic radiation proctitis: a randomized double blind trial Colorectal Disease. ,vol. 15, pp. e48- e55 ,(2013) , 10.1111/CODI.12035
AA Alfadhli, WM Alazmi, T Ponich, JM Howard, I Prokopiw, A Alaqeel, JC Gregor, Efficacy of Argon Plasma Coagulation Compared with Topical Formalin Application for Chronic Radiation Proctopathy Canadian Journal of Gastroenterology & Hepatology. ,vol. 22, pp. 129- 132 ,(2008) , 10.1155/2008/964912
E. Rubinstein, T. Ibsen, R.B. Rasmussen, B.L. Sorensen, E. Reimer, Formalin treatment of radiation-induced hemorrhagic proctitis. The American Journal of Gastroenterology. ,vol. 81, pp. 44- 45 ,(1986)
Abdul Rahim Mohd Tahir, Justin Westhuyzen, Joshua Dass, Michael K Collins, Robert Webb, Susan Hewitt, Peter Fon, Michael McKay, Hyperbaric oxygen therapy for chronic radiation-induced tissue injuries: Australasia's largest study. Asia-pacific Journal of Clinical Oncology. ,vol. 11, pp. 68- 77 ,(2015) , 10.1111/AJCO.12289
D C Warren, J B Slade, P E Cianci, P Feehan, Chronic radiation proctitis treated with hyperbaric oxygen. Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society. ,vol. 24, pp. 181- 184 ,(1997)
Pedro Luna-Pérez, Saúl E. Rodríguez-Ramírez, Formalin instillation for refractory radiation-induced hemorrhagic proctitis. Journal of Surgical Oncology. ,vol. 80, pp. 41- 44 ,(2002) , 10.1002/JSO.10095
Fouad J. Moawad, Corinne L. Maydonovitch, J David Horwhat, Efficacy of cryospray ablation for the treatment of chronic radiation proctitis in a pilot study Digestive Endoscopy. ,vol. 25, pp. 174- 179 ,(2013) , 10.1111/J.1443-1661.2012.01355.X