Localization of the human erbB-2 gene on normal and rearranged chromosomes 17 to bands q12–21.32
作者： Nicholas C. Popescu , C.Richter King , Matthias H. Kraus
DOI: 10.1016/0888-7543(89)90343-1
关键词: Hybridization probe 、 Chromosome 15 、 In situ hybridization 、 Chromosomal translocation 、 Complementary DNA 、 Chromosome 、 Biology 、 Gene 、 Prophase 、 Molecular biology 、 Genetics
摘要: Through the use of a cDNA probe, human erbB-2 gene was localized by in situ hybridization normal chromosomes at 17q11-q21. In derived from fibroblasts carrying constitutional 15;17t(q22.3;q11.21) translocation showed that relocated on rearranged chromosome 15. These results as well grain localization prophase locate 17q12-q21.32. This may facilitate search for malignancies with changes involving gene.
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sci-hub.se 参考文章(22)
Matthias H. Kraus, Pier Paolo Di Fiore, Jacalyn H. Pierce, Stuart A. Aaronson, Different mechanisms are responsible for oncogene activation in human mammary neoplasia. Cancer treatment and research. ,vol. 40, pp. 49- 66 ,(1988) , 10.1007/978-1-4613-1733-3_3
M.H. Kraus, N.C. Popescu, S.C. Amsbaugh, C.R. King, Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms The EMBO Journal. ,vol. 6, pp. 605- 610 ,(1987) , 10.1002/J.1460-2075.1987.TB04797.X
Carlo M. Croce, Peter C. Nowell, Molecular Basis of Human B Cell Neoplasia RNA Tumor Viruses, Oncogenes, Human Cancer and AIDS: On the Frontiers of Understanding. ,vol. 65, pp. 116- 126 ,(1985) , 10.1007/978-1-4613-2583-3_10
S Fukushige, K Matsubara, M Yoshida, M Sasaki, T Suzuki, K Semba, K Toyoshima, T Yamamoto, Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line Molecular and Cellular Biology. ,vol. 6, pp. 955- 958 ,(1986) , 10.1128/MCB.6.3.955
A. I. Dayton, J. R. Selden, G. Laws, D. J. Dorney, J. Finan, P. Tripputi, B. S. Emanuel, G. Rovera, P. C. Nowell, C. M. Croce, A human c-erbA oncogene homologue is closely proximal to the chromosome 17 breakpoint in acute promyelocytic leukemia Proceedings of the National Academy of Sciences of the United States of America. ,vol. 81, pp. 4495- 4499 ,(1984) , 10.1073/PNAS.81.14.4495
P. Di Fiore, J. Pierce, M. Kraus, O Segatto, C. King, S. Aaronson, erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells Science. ,vol. 237, pp. 178- 182 ,(1987) , 10.1126/SCIENCE.2885917
S. Weil, G. Rosner, M. Reid, R. Chisholm, R. Lemons, M. Swanson, J. Carrino, M. Diaz, M. Le Beau, Translocation and rearrangement of myeloperoxidase gene in acute promyelocytic leukemia. Science. ,vol. 240, pp. 790- 792 ,(1988) , 10.1126/SCIENCE.2896388
C. King, M. Kraus, S. Aaronson, Amplification of a novel v-erbB-related gene in a human mammary carcinoma Science. ,vol. 229, pp. 974- 976 ,(1985) , 10.1126/SCIENCE.2992089
F. Mitelman, G. Manolov, Y. Manolova, R. Billström, S. Heim, U. Kristoffersson, N. Mandahl, M.T. Ferro, C. San Roman, High resolution chromosome analysis of constitutional and acquired t(15;17) maps c-erbA to Subband 17q11.2 Cancer Genetics and Cytogenetics. ,vol. 22, pp. 95- 98 ,(1986) , 10.1016/0165-4608(86)90168-8
K. Semba, N. Kamata, K. Toyoshima, T. Yamamoto, A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma Proceedings of the National Academy of Sciences of the United States of America. ,vol. 82, pp. 6497- 6501 ,(1985) , 10.1073/PNAS.82.19.6497