High resolution chromosome analysis of constitutional and acquired t(15;17) maps c-erbA to Subband 17q11.2
作者： F. Mitelman , G. Manolov , Y. Manolova , R. Billström , S. Heim
DOI: 10.1016/0165-4608(86)90168-8
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摘要: High resolution chromosome analysis was performed on bone marrow cells from four patients with acute promyelocytic leukemia and t(15;17), in lymphocytes two unrelated, phenotypically normal persons an apparently identical constitutional translocation. Scrutiny of prophase-prometaphase chromosomes localized the breakpoints all six cases to subbands 15q22.3 17q11.2. Molecular genetic studies have oncogene c-erbA #17 between acquired anomaly. The present results, therefore, map subband
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