Coronary microvascular dysfunction is highly prevalent in women with chest pain in the absence of coronary artery disease: Results from the NHLBI WISE study

作者: Steven E. Reis , Richard Holubkov , A.J.Conrad Smith , Sheryl F. Kelsey , Barry L. Sharaf

DOI: 10.1067/MHJ.2001.114198

关键词: Cardiac catheterizationHeart diseaseMicroangiopathyCoronary circulationCardiologyCoronary artery diseaseCoronary vesselThoraxMedicineInternal medicineChest pain

摘要: Background Chest pain in the absence of obstructive coronary artery disease (CAD) is common in women; it is frequently associated with debilitating symptoms and repeated evaluations and may be caused by coronary microvascular dysfunction. However, the prevalence and determinants of microvascular dysfunction in these women are uncertain. Methods We measured coronary flow velocity reserve (coronary velocity response to intracoronary adenosine) to evaluate the coronary microvasculature and risk factors for …

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