Mitochondrial Replacement Therapies Can Circumvent mtDNA-Based Disease Transmission
作者： Don P. Wolf , Shoukhrat Mitalipov
DOI: 10.1016/J.CMET.2014.06.012
关键词: Transmission (medicine) 、 Mitochondrial DNA 、 Mitochondrial disease 、 Genome 、 Disease transmission 、 Biology 、 Polar body 、 Genetics
摘要: Mitochondrial DNA diseases are relatively common, sometimes devastating, and transmitted exclusively through the egg to children of carrier mothers. A study in Cell by Wang et al. (2014) adds exciting possibility a new therapy for preventing mitochondrial disease transmission predicated on use polar body genomes mice.
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