Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma
作者： Christian Karagiannidis , Mübeccel Akdis , Päivi Holopainen , Niina J Woolley , Gabriele Hense
DOI: 10.1016/J.JACI.2004.07.014
关键词: Regulatory T cell 、 Peripheral tolerance 、 Endocrinology 、 Internal medicine 、 Interleukin 21 、 Cytotoxic T cell 、 Interleukin 10 、 Immunology 、 IL-2 receptor 、 FOXP3 、 Biology 、 Glucocorticoid
摘要: … FOXP3 and IL10 in CD4 + T cells of asthmatic patients and healthy donors and the effect of glucocorticoids on T reg cells … the transcription factor FOXP3 and generate T reg cells of the T …
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Robert S. Wildin, Fred Ramsdell, Jane Peake, Francesca Faravelli, Jean-Laurent Casanova, Neil Buist, Ephrat Levy-Lahad, Massimo Mazzella, Olivier Goulet, Lucia Perroni, Franca Dagna Bricarelli, Geoffrey Byrne, Mark McEuen, Sean Proll, Mark Appleby, Mary E. Brunkow, X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nature Genetics. ,vol. 27, pp. 18- 20 ,(2001) , 10.1038/83707
Hervé Groux, Anne O'Garra, Mike Bigler, Matthieu Rouleau, Svetlana Antonenko, Jan E. de Vries, Maria Grazia Roncarolo, A CD4 + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis Nature. ,vol. 389, pp. 737- 742 ,(1997) , 10.1038/39614
C. B. Schmidt-Weber, A. H. Lichtman, S. I. Alexander, L. James, L. E. Henault, IL-4 Enhances IL-10 Gene Expression in Murine Th2 Cells in the Absence of TCR Engagement Journal of Immunology. ,vol. 162, pp. 238- 244 ,(1999)
Zieg, Lack, Harbeck, Gelfand, Leung, In vivo effects of glucocorticoids on IgE production The Journal of Allergy and Clinical Immunology. ,vol. 94, pp. 222- 230 ,(1994) , 10.1053/AI.1994.V94.A54936
P D Walzer, M T Cushion, M LaBine, T J Redington, Lymphocyte changes during chronic administration of and withdrawal from corticosteroids: relation to Pneumocystis carinii pneumonia. Journal of Immunology. ,vol. 133, pp. 2502- 2508 ,(1984)
Richard A. Miller, Richard A. Miller, Igor M. Dozmorov, Generation of antigen-specific Th2 cells from unprimed mice in vitro: effects of dexamethasone and anti-IL-10 antibody. Journal of Immunology. ,vol. 160, pp. 2700- 2705 ,(1998)
Kian Fan Chung, P Godard, E Adelroth, J Ayres, N Barnes, P Barnes, E Bel, P Burney, P Chanez, G Connett, C Corrigan, J De Blic, Leonardo Fabbri, ST Holgate, P Ind, Guy Joos, H Kerstjens, P Leuenberger, CG Lofdahl, S McKenzie, H Magnussen, D Postma, Marina Saetta, S Salmeron, P Sterk, Difficult/therapy-resistant asthma: the need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel therapies. ERS Task Force on Difficult/Therapy-Resistant Asthma. European Respiratory Society European Respiratory Journal. ,vol. 13, pp. 1198- 1208 ,(1999) , 10.1034/J.1399-3003.1999.13E43.X
Hideki Miyaura, Makoto Iwata, Direct and Indirect Inhibition of Th1 Development by Progesterone and Glucocorticoids Journal of Immunology. ,vol. 168, pp. 1087- 1094 ,(2002) , 10.4049/JIMMUNOL.168.3.1087
P. Putheti, M. Morris, L. Stawiarz, N. Teleshova, P. Kivisäkk, M. Pashenkov, M. Kouwenhoven, M. K. Wiberg, L. Bronge, Y.-M. Huang, M. Söderström, J. Hillert, H. Link, Multiple sclerosis: a study of chemokine receptors and regulatory T cells in relation to MRI variables. European Journal of Neurology. ,vol. 10, pp. 529- 535 ,(2003) , 10.1046/J.1468-1331.2003.00638.X
S. Kunzmann, J. G. Wohlfahrt, S. Itoh, H. Asao, M. Komada, C. A. Akdis, K. Blaser, C. B. Schmidt‐Weber, SARA and Hgs attenuate susceptibility to TGF-β1-mediated T cell suppression The FASEB Journal. ,vol. 17, pp. 194- 202 ,(2003) , 10.1096/FJ.02-0550COM