A cytogenetic study of repeated spontaneous abortions.

摘要: During a cytogenetic study of spontaneous abortions, successive abortions from 40 couples were karyotyped. The chromosome constitutions the first and second found to be highly correlated. In each 21 instances in which abortion was chromosomally normal, subsequent abortion(s) normal as well. nine cases, two abnormal, four these, both trisomic. Combined with findings other studies consecutive present data indicate that certain are at an increased risk for either repeated or trisomic conceptions. trisomy does not seem restricted particular chromosome, magnitude increase appears independent maternal age.