Expression and function of cell cycle proteins in rheumatoid arthritis synovial tissue.
作者： Michelle Theresa Leech , Elliott Taranto
DOI: 10.14670/HH-21.205
关键词: Apoptosis 、 Medicine 、 Homeostasis 、 Pathological 、 Rheumatoid arthritis 、 Arthritis 、 Hyperplasia 、 Cell Cycle Protein 、 Pathology 、 Cell cycle
摘要: Summary. Rheumatoid Arthritis (RA) is a chronic disease characterised by synovial lining hyperplasia and progressive destruction of joint tissues. Experimental data suggests that abnormal alterations in the expression proteins involved maintaining homeostatic control cell cycle progression RA. By contributing to overgrowth tissue, factors such as dysregulated proliferation or reduced apoptosis cells can directly influence pathological outcome Histol Histopathol 21, 205-211 (2006)
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