Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression

作者: Etsu Tashiro , Ayako Tsuchiya , Masaya Imoto

DOI: 10.1111/J.1349-7006.2007.00449.X

关键词: Cyclin ABiologyCyclin ECyclin A2Cyclin D1Cyclin-dependent kinase complexCyclin BCancer researchCyclin-dependent kinaseCyclin DOncologyGeneral Medicine

摘要: … of cyclin D1 in fibroblast cultures shortens the G1 phase of the cell cycle. Furthermore, it has been demonstrated that introduction of an antisense cyclin D1 … The pRB/E2F pathway has …

参考文章(49)
Tony Kouzarides, Peter Angel, Dagmar Wilhelm, Andrew J. Bannister, Thomas Oehler, Thomas Oehler, Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro. Oncogene. ,vol. 11, pp. 2509- 2514 ,(1995)
R. M. Santella, Yu-Jing Zhang, S. Doi, A. S. Infante, S. M. Kahn, I. B. Weinstein, A. M. Cacace, Wei Jiang, Ping Zhou, Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression. Oncogene. ,vol. 8, pp. 3447- 3457 ,(1993)
Yoshiaki Kumon, Saburo Sakaki, Katsuyuki Hamada, Kohji Sato, Kou Nakagawa, Hironobu Harada, Shinji Iwata, Masahiro Saito, Restoration of wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas. Cancer Research. ,vol. 59, pp. 3783- 3789 ,(1999)
Catherine Gratas, Hiroko Ohgaki, Pierre Hainaut, Philippe Taniere, Christoph Barnas, Yasuo Tohma, Up-regulation of Fas (APO-1/CD95) ligand and down-regulation of Fas expression in human esophageal cancer. Cancer Research. ,vol. 58, pp. 2057- 2062 ,(1998)
K. Nishi, M. Yoshida, D. Fujiwara, M. Nishikawa, S. Horinouchi, T. Beppu, Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression. Journal of Biological Chemistry. ,vol. 269, pp. 6320- 6324 ,(1994) , 10.1016/S0021-9258(17)37374-X
Lance A. Liotta, Elise C. Kohn, The microenvironment of the tumour-host interface Nature. ,vol. 411, pp. 375- 379 ,(2001) , 10.1038/35077241
T. Delohery, A. Sgambato, Y. Doki, M. G. Klein, P. R. Holt, E. K.-H. Han, I. B. Weinstein, N. Arber, N.-H. Kim, P. Zhou, Antisense to Cyclin D1 Inhibits the Growth and Tumorigenicity of Human Colon Cancer Cells Cancer Research. ,vol. 57, pp. 1569- 1574 ,(1997)
D Resnitzky, M Gossen, H Bujard, S I Reed, Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. Molecular and Cellular Biology. ,vol. 14, pp. 1669- 1679 ,(1994) , 10.1128/MCB.14.3.1669
S W.K. AL-MURRANI, James R. WOODGETT, Zahi DAMUNI, Expression of I2PP2A, an inhibitor of protein phosphatase 2A, induces c-Jun and AP-1 activity Biochemical Journal. ,vol. 341, pp. 293- 298 ,(1999) , 10.1042/BJ3410293