Short Hairpin RNA (shRNA) Ether à go-go 1 (Eag1) Inhibition of Human Osteosarcoma Angiogenesis via VEGF/PI3K/AKT Signaling

作者: Jin Wu , Xinyu Wu , Daixing Zhong , Wenliang Zhai , Zhenqi Ding

DOI: 10.3390/IJMS131012573

关键词: OsteosarcomaVascular endothelial growth factor AMedicineProtein kinase BPathologySmall hairpin RNAAngiogenesisPI3K/AKT/mTOR pathwayVascular endothelial growth factorCancer researchGene silencing

摘要: … To address the detail mechanisms of tumor inhibition induced by Eag1 silencing, we focused on angiogenesis. We found that Eag1 silencing not only suppressed angiogenesis in …

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