The structure of the capsular polysaccharide (K5 antigen) of urinary-tract-infective Escherichia coli 010:K5:H4. A polymer similar to desulfo-heparin.
作者： Willie F. VANN , M. Alexander SCHMIDT , Barbara JANN , Klaus JANN
DOI: 10.1111/J.1432-1033.1981.TB05343.X
关键词: Nuclear magnetic resonance spectroscopy 、 Biochemistry 、 Escherichia coli 、 Deamination 、 Glucuronic acid 、 Disaccharide 、 Acid hydrolysis 、 Polysaccharide 、 Mutant 、 Chemistry
摘要: The capsular polysaccharide was isolated from Escherichia coli 010:K5:H4; it could not be obtained a uncapsulated (K5-) mutant. It contains N-acetylglucosamine and glucuronic acid in molar ratio of 1:1. Acid hydrolysis the acidic as well Smith degradation by deamination carboxyl-reduced suggested that is composed disaccharide repeating unit. data methylation analysis nuclear magnetic resonance spectroscopy indicated sequence 4-beta-glucuronyl-1,4-alpha-N-acetylglucosaminyl This structure similar to desulfo-heparin.
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