Receptor Protein Tyrosine Phosphatase From Stem Cells to Mature Glial Cells of the Central Nervous System
作者： Smaragda Lamprianou , Sheila Harroch
DOI: 10.1385/JMN:29:3:241
关键词: Cellular differentiation 、 Cell biology 、 Neuroepithelial cell 、 Mitogen-activated protein kinase 、 Phosphorylation 、 Stem cell 、 Cell signaling 、 Protein tyrosine phosphatase 、 Receptor tyrosine kinase 、 Biology 、 Cellular and Molecular Neuroscience 、 General Medicine
摘要: The cornerstone of cell signaling is largely based on the phosphorylation state that defined by equilibrium activity protein kinases and phosphatases. role tyrosine in brain development, tumors, neurodegenerative diseases was studied extensively, yet, importance phosphatases (PTPs) development glial cells somewhat neglected. In this review, we have summarized recent findings PTP expression during central nervous system different types brain, from stem to mature cells, highlighted potential these enzymes neuronal glioblastomas, myelination.
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