Functional importance of RASSF1A microtubule localization and polymorphisms
作者： M El-Kalla , C Onyskiw , S Baksh
DOI: 10.1038/ONC.2010.316
关键词: Carcinogenesis 、 Cancer research 、 Apoptosis 、 Molecular biology 、 Biology 、 Tumor suppressor gene 、 Nude mouse 、 Tubulin 、 Suppressor 、 Methylation 、 Microtubule
摘要: … a role for RASSF1A microtubule localization in eliciting its tumor suppressor function. … association of RASSF1A with tubulin, we carried out cell-cycle arrest in S phase with the addition of …
nature.com
sci-hub.se 
researchgate.net 参考文章(46)
Dammann R, Strunnikova M, Pfeifer Gp, Rastetter M, Seidel C, Schagdarsurengin U, Baier K, The tumor suppressor RASSF1A in human carcinogenesis: an update. Histology and Histopathology. ,vol. 20, pp. 645- 663 ,(2005) , 10.14670/HH-20.645
E R Fernandes, R J Rooney, The adenovirus E1A-regulated transcription factor E4F is generated from the human homolog of nuclear factor phiAP3. Molecular and Cellular Biology. ,vol. 17, pp. 1890- 1903 ,(1997) , 10.1128/MCB.17.4.1890
M. Adachi, Yu-Bin Zhang, K. Imai, Mutation of BAD within the BH3 domain impairs its phosphorylation-mediated regulation FEBS Letters. ,vol. 551, pp. 147- 152 ,(2003) , 10.1016/S0014-5793(03)00915-3
Maria PRASKOVA, Andrei KHOKLATCHEV, Sara ORTIZ-VEGA, Joseph AVRUCH, Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras. Biochemical Journal. ,vol. 381, pp. 453- 462 ,(2004) , 10.1042/BJ20040025
Anna Moshnikova, Judson Frye, Jerry W. Shay, John D. Minna, Andrei V. Khokhlatchev, The Growth and Tumor Suppressor NORE1A Is a Cytoskeletal Protein That Suppresses Growth by Inhibition of the ERK Pathway Journal of Biological Chemistry. ,vol. 281, pp. 8143- 8152 ,(2006) , 10.1074/JBC.M511837200
Lara Cuschieri, Thao Nguyen, Jackie Vogel, Control at the cell center: the role of spindle poles in cytoskeletal organization and cell cycle regulation. Cell Cycle. ,vol. 6, pp. 2788- 2794 ,(2007) , 10.4161/CC.6.22.4941
Haya Abu Ghazaleh, Renfred S. Chow, Sheryl L. Choo, Diana Pham, Jamie D. Olesen, Russell X. Wong, Christina Onyskiw, Shairaz Baksh, 14-3-3 mediated regulation of the tumor suppressor protein, RASSF1A. Apoptosis. ,vol. 15, pp. 117- 127 ,(2010) , 10.1007/S10495-009-0451-6
N P C Allen, H Donninger, M D Vos, K Eckfeld, L Hesson, L Gordon, M J Birrer, F Latif, G J Clark, RASSF6 is a novel member of the RASSF family of tumor suppressors. Oncogene. ,vol. 26, pp. 6203- 6211 ,(2007) , 10.1038/SJ.ONC.1210440
Garth Hamilton, Karen S. Yee, Simon Scrace, Eric O'Neill, ATM regulates a RASSF1A-dependent DNA damage response. Current Biology. ,vol. 19, pp. 2020- 2025 ,(2009) , 10.1016/J.CUB.2009.10.040
Boning Gao, Xian-Jin Xie, Chunxian Huang, David S. Shames, Tina T-L. Chen, Cheryl M. Lewis, Aihua Bian, Bifeng Zhang, Olufunmilayo I. Olopade, Judy E. Garber, David M. Euhus, Gail E. Tomlinson, John D. Minna, RASSF1A polymorphism A133S is associated with early onset breast cancer in BRCA1/2 mutation carriers. Cancer Research. ,vol. 68, pp. 22- 25 ,(2008) , 10.1158/0008-5472.CAN-07-5183