Receptors for C3 on B Lymphocytes: Possible Role in the Immune Response

摘要: Publisher Summary This chapter discusses the possible role of receptors for C3 on B lymphocytes in immune response. Complement–receptor (CRLs) have been defined as a population lymphoid cells found many mammalian species, including man, which is capable binding antigen–antibody–complement complexes through membrane receptor modified complement component (C3). CRL can be readily identified and isolated by virtue their ability to form rosettes with sheep erythrocytes that sensitized rabbit antibody against Forssmann antigen complement. characteristic distribution organs thatgrossly coincides carrying easily detectable immunoglobulin (Ig) determinants membranes. They are absent from thymus large numbers among lymph nodes, spleen, thoracic duct normal mice. The differences between mononuclear phagocytes. It also describes function lymphocytes.