Specialized dendritic cells induce tumor-promoting IL-10 + IL-17 + FoxP3 neg regulatory CD4 + T cells in pancreatic carcinoma
作者： Rocky M. Barilla , Brian Diskin , Raul Caso Caso , Ki Buom Lee , Navyatha Mohan
DOI: 10.1038/S41467-019-09416-2
关键词: Chemistry 、 FOXP3 、 Interleukin 17 、 T cell differentiation 、 T cell 、 Cellular differentiation 、 Cancer research 、 Interleukin 10 、 Tumor microenvironment 、 Immunotherapy
摘要: … Single-cell suspensions for flow cytometry were prepared as we described previously 18,19 . Briefly, PDA tumors were placed in cold RPMI-1640 with Collagenase IV (1 mg/mL; …
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