Cellular differentiation in three-dimensional lung cell cultures.
作者： Roger A. Vertrees , Joseph B. Zwischenberger , Paul J. Boor , Vselovod Popov , Maureen McCarthy
DOI: 10.4161/CBT.7.3.5368
关键词: Current cell 、 Organelle 、 Cellular differentiation 、 Lung 、 Biology 、 Normal lung 、 Cell culture 、 Immortalised cell line 、 Tissue engineering 、 Cell biology
摘要: Introduction: Aspects of human biology that are not sufficiently addressed by current cell culture models cellular differentiation and three-dimensional (3-D) structural organization. A model more closely associates the presence organelles to molecular expressions relevant these may provide evidence beginning steps in construction a 3-D architecture. The development new — cultures ultimately better understanding lung pathobiology. Purpose: purpose this study was develop both traditional monolayer known well documented normal line then determine similarities differences between terms marker expression. Methods: An immortalized grown as (ML) flasks rotating walled vessels incubated under iden...
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