Human Papilloma Virus' Life Cycle and Carcinogenesis.
作者： Georgios Galazios , Panagiotis Tsikouras , Zacharoula Koukouli , Stefanos Zervoudis , Simona Vladareanu
DOI:
关键词: Oncology 、 Human papilloma virus 、 Clearance 、 Lower genital tract 、 Cell cycle 、 Medicine 、 Cervical cancer 、 Carcinogenesis 、 Cancer incidence 、 Cervical carcinogenesis 、 Internal medicine
摘要: Rationale Considering that the loss of cell cycle and apoptosis control constitutes a central event in human papilloma virus' (HPV)-mediated carcinogenesis, reason this study is to insight HPV life cycle. Objective The purpose analyze molecular biology cervical cancer association. Methods results Brief review current literature on carcinogenesis. Discussion Among associated cancers, still ranks number two global incidence women. A component association between carcinogenesis ability persist lower genital tract for long periods time without being cleared because its evasion mechanisms.
参考文章(25)
Gülçin Alp Avcı, Genomic organization and proteins of human papillomavirus Mikrobiyoloji Bulteni. ,vol. 46, pp. 507- 515 ,(2012)
Melanie McFarlane, Sheila V. Graham, Human papillomavirus regulation of SR proteins. Biochemical Society Transactions. ,vol. 38, pp. 1116- 1121 ,(2010) , 10.1042/BST0381116
Patrick S. Moore, Yuan Chang, Why do viruses cause cancer? Highlights of the first century of human tumour virology Nature Reviews Cancer. ,vol. 10, pp. 878- 889 ,(2010) , 10.1038/NRC2961
Juliane Haedicke, Thomas Iftner, Human papillomaviruses and cancer. Radiotherapy and Oncology. ,vol. 108, pp. 397- 402 ,(2013) , 10.1016/J.RADONC.2013.06.004
Arnold J. Levine, The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53. Virology. ,vol. 384, pp. 285- 293 ,(2009) , 10.1016/J.VIROL.2008.09.034
Daniel DiMaio, Lisa M. Petti, The E5 proteins Virology. ,vol. 445, pp. 99- 114 ,(2013) , 10.1016/J.VIROL.2013.05.006
Alison A. McBride, The Papillomavirus E2 proteins Virology. ,vol. 445, pp. 57- 79 ,(2013) , 10.1016/J.VIROL.2013.06.006
Vijayalakshmi Ramshankar, Arvind Krishnamurthy, Human Papilloma Virus in Head and Neck Cancers—Role and Relevance in Clinical Management Indian Journal of Surgical Oncology. ,vol. 4, pp. 59- 66 ,(2013) , 10.1007/S13193-012-0196-5
Karl Münger, John R Basile, Stefan Duensing, Alexandra Eichten, Sonia L Gonzalez, Miranda Grace, Valerie L Zacny, Biological activities and molecular targets of the human papillomavirus E7 oncoprotein Oncogene. ,vol. 20, pp. 7888- 7898 ,(2001) , 10.1038/SJ.ONC.1204860
T. O. Garnett, P. J. Duerksen-Hughes, Modulation of apoptosis by human papillomavirus (HPV) oncoproteins. Archives of Virology. ,vol. 151, pp. 2321- 2335 ,(2006) , 10.1007/S00705-006-0821-0