Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes
作者： Marcus Bantscheff , Carsten Hopf , Mikhail M Savitski , Antje Dittmann , Paola Grandi
DOI: 10.1038/NBT.1759
关键词: Chemoproteomics 、 Chemistry 、 Biochemistry 、 HDAC10 、 Mitosis 、 Histone deacetylase inhibitor 、 HDAC inhibitor 、 Small molecule 、 Histone deacetylase 、 HDAC6
摘要: … To differentiate between novel direct targets and novel components of HDAC complexes, we carried out a series of co-immunoprecipitations (co-IP) with quantitative MS/MS analysis. …
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