C3 Sulfenylation of N‐Heteroarenes in Water under Catalyst‐Free Conditions
作者： Chitrakar Ravi , Abhisek Joshi , Subbarayappa Adimurthy
关键词: Organic solvent 、 Chemistry 、 Reagent 、 Catalysis 、 Organic chemistry 、 Functional group 、 Aqueous medium 、 Water chemistry 、 Sulfur
摘要: We describe herein a catalyst-free selective C−H sulfenylation of imidazo[1,2-a]pyridines using sulfonothioates as odorless source thioarylated reagent in an aqueous medium. The method works for variety substituted with broad functional group tolerance. methodology has been extends to sulfernylation indoles and imidazothiazoles. are activated exclusively medium rather than organic solvent media the feasibility process scale-up studies have demonstrated.
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