Development of human mesenchymal stem cells on DC sputtered titanium nitride thin films.
作者： M. Manso-Silvan , J. M. Martínez-Duart , S. Ogueta , P. García-Ruiz , J. Pérez-Rigueiro
关键词: Biomaterial 、 Titanium nitride 、 Nanoindentation 、 Thin film 、 Tin 、 Nanotechnology 、 Sheet resistance 、 Sputter deposition 、 Materials science 、 Scanning electron microscope
摘要: The biocompatible properties of titanium nitride (TiN) have opened a new field applications for this material. In the present work, TiN coatings with thicknesses around 1 μm been prepared by DC magnetron sputtering. aim has to evaluate adherence, growth and proliferation human pluripotent mesenchymal stem cells (hMSCs) on surface films contrasted structural, electrical, mechanical properties. For purpose, were characterized X-ray diffraction, scanning electron microscopy, sheet resistance measurements, nanoindentation. Biological tests show that hMSCs adhere proliferate onto surfaces. combination mechanical, biological responses suggest appropriate induce in vitro stimulated differentiation hMSCs. This possibility gives an added value based biomaterial coatings.
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