Of Brains and Blood: Developmental Origins of Glioma Diversity?

作者: Mariella G Filbin , Charles D Stiles

DOI: 10.1016/J.CCELL.2015.09.013

关键词: Progenitor cellAdult stem cellCentral nervous systemCell typeImmunologyGliomaInduced pluripotent stem cellGlioblastomaCancer cellNeuroscienceBiology

摘要: The multiple cell types of brain and blood arise from pluripotent stem cells via progressively more committed downstream progenitors. In this issue Cancer Cell, Alcantara Llaguno colleagues show that identical genetic drivers give rise to distinct glioma subtypes within differentially neural progenitors-a paradigm well established for leukemias.

参考文章(11)
David N. Louis, Arie Perry, Peter Burger, David W. Ellison, Guido Reifenberger, Andreas von Deimling, Kenneth Aldape, Daniel Brat, V. Peter Collins, Charles Eberhart, Dominique Figarella-Branger, Gregory N. Fuller, Felice Giangaspero, Caterina Giannini, Cynthia Hawkins, Paul Kleihues, Andrey Korshunov, Johan M. Kros, M. Beatriz Lopes, Ho-Keung Ng, Hiroko Ohgaki, Werner Paulus, Torsten Pietsch, Marc Rosenblum, Elisabeth Rushing, Figen Soylemezoglu, Otmar Wiestler, Pieter Wesseling, International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading Brain Pathology. ,vol. 24, pp. 429- 435 ,(2014) , 10.1111/BPA.12171
D. Friedmann-Morvinski, E. A. Bushong, E. Ke, Y. Soda, T. Marumoto, O. Singer, M. H. Ellisman, I. M. Verma, Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice. Science. ,vol. 338, pp. 1080- 1084 ,(2012) , 10.1126/SCIENCE.1226929
Thomas S Jacques, Alexander Swales, Monika J Brzozowski, Nico V Henriquez, Jacqueline M Linehan, Zaman Mirzadeh, Catherine O' Malley, Heike Naumann, Arturo Alvarez-Buylla, Sebastian Brandner, Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes The EMBO Journal. ,vol. 29, pp. 222- 235 ,(2010) , 10.1038/EMBOJ.2009.327
Richard J. Gilbertson, Jeremy N. Rich, Making a tumour's bed: glioblastoma stem cells and the vascular niche Nature Reviews Cancer. ,vol. 7, pp. 733- 736 ,(2007) , 10.1038/NRC2246
Rui Pedro Galvao, Anita Kasina, Robert S. McNeill, Jordan E. Harbin, Oded Foreman, Roel G. W. Verhaak, Akiko Nishiyama, C. Ryan Miller, Hui Zong, Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process Proceedings of the National Academy of Sciences of the United States of America. ,vol. 111, pp. 201414389- ,(2014) , 10.1073/PNAS.1414389111
Roger Stupp, Warren P. Mason, Martin J. van den Bent, Michael Weller, Barbara Fisher, Martin J.B. Taphoorn, Karl Belanger, Alba A. Brandes, Christine Marosi, Ulrich Bogdahn, Jürgen Curschmann, Robert C. Janzer, Samuel K. Ludwin, Thierry Gorlia, Anouk Allgeier, Denis Lacombe, J. Gregory Cairncross, Elizabeth Eisenhauer, René O. Mirimanoff, Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma The New England Journal of Medicine. ,vol. 352, pp. 987- 996 ,(2005) , 10.1056/NEJMOA043330
Brady Bernard, Chang-Jiun Wu, Giannicola Genovese, Ilya Shmulevich, Jill Barnholtz-Sloan, Lihua Zou, Rahulsimham Vegesna, Sachet A. Shukla, Giovanni Ciriello, W.K. Yung, Wei Zhang, Carrie Sougnez, Tom Mikkelsen, Kenneth Aldape, Darell D. Bigner, Erwin G. Van Meir, Michael Prados, Andrew Sloan, Keith L. Black, Jennifer Eschbacher, Gaetano Finocchiaro, William Friedman, David W. Andrews, Abhijit Guha, Mary Iacocca, Brian P. O’Neill, Greg Foltz, Jerome Myers, Daniel J. Weisenberger, Robert Penny, Raju Kucherlapati, Charles M. Perou, D. Neil Hayes, Richard Gibbs, Marco Marra, Gordon B. Mills, Eric Lander, Paul Spellman, Richard Wilson, Chris Sander, John Weinstein, Matthew Meyerson, Stacey Gabriel, Peter W. Laird, David Haussler, Gad Getz, Lynda Chin, Christopher Benz, Jill Barnholtz-Sloan, Wendi Barrett, Quinn Ostrom, Yingli Wolinsky, Keith L. Black, Bikash Bose, Paul T. Boulos, Madgy Boulos, Jenn Brown, Christine Czerinski, Matthew Eppley, Mary Iacocca, Thelma Kempista, Teresa Kitko, Yakov Koyfman, Brenda Rabeno, Pawan Rastogi, Michael Sugarman, Patricia Swanson, Kennedy Yalamanchii, Ilana P. Otey, Yingchun Spring Liu, Yonghong Xiao, J.Todd Auman, Peng-Chieh Chen, Angela Hadjipanayis, Eunjung Lee, Semin Lee, Peter J. Park, Jonathan Seidman, Lixing Yang, Raju Kucherlapati, Steven Kalkanis, Tom Mikkelsen, Laila M. Poisson, Aditya Raghunathan, Lisa Scarpace, Brady Bernard, Ryan Bressler, Andrea Eakin, Lisa Iype, Richard B. Kreisberg, Kalle Leinonen, Sheila Reynolds, Hector Rovira, Vesteinn Thorsson, Ilya Shmulevich, Matti J. Annala, Robert Penny, Joseph Paulauskis, Erin Curley, Martha Hatfield, David Mallery, Scott Morris, Troy Shelton, Candace Shelton, Mark Sherman, Peggy Yena, Lucia Cuppini, Francesco DiMeco, Marica Eoli, Gaetano Finocchiaro, Emanuela Maderna, Bianca Pollo, Marco Saini, Saianand Balu, Katherine A. Hoadley, Ling Li, C. Ryan Miller, Yan Shi, Michael D. Topal, Junyuan Wu, Gavin Dunn, Caterina Giannini, Brian P. O'Neill, B. Arman Aksoy, Yevgeniy Antipin, Laetitia Borsu, Samuel H. Berman, Cameron W. Brennan, Cameron W. Brennan, Roel G.W. Verhaak, Aaron McKenna, Benito Campos, Houtan Noushmehr, Sofie R. Salama, Siyuan Zheng, Debyani Chakravarty, J. Zachary Sanborn, Samuel H. Berman, Rameen Beroukhim, Wenbin Liu, Yuexin Liu, Yiling Lu, Gordon Mills, Alexei Protopopov, Xiaojia Ren, Youting Sun, Chang-Jiun Wu, W.K. Alfred Yung, Wei Zhang, Jianhua Zhang, Ken Chen, John N. Weinstein, Lynda Chin, Roel G.W. Verhaak, Houtan Noushmehr, Daniel J. Weisenberger, Moiz S. Bootwalla, Phillip H. Lai, Timothy J. Triche, David J. Van Den Berg, Peter W. Laird, David H. Gutmann, Norman L. Lehman, Erwin G. VanMeir, Daniel Brat, Jeffrey J. Olson, Gena M. Mastrogianakis, Narra S. Devi, Zhaobin Zhang, Darell Bigner, Eric Lipp, Roger McLendon, Ethan Cerami, Debyani Chakravarty, Giovanni Ciriello, Jianjiong Gao, Benjamin Gross, Anders Jacobsen, Marc Ladanyi, Alex Lash, Yupu Liang, Boris Reva, Chris Sander, Nikolaus Schultz, Ronglai Shen, Nicholas D. Socci, Agnes Viale, Martin L. Ferguson, Qing-Rong Chen, John A. Demchok, Laura A.L. Dillon, Kenna R. Mills Shaw, Margi Sheth, Roy Tarnuzzer, Zhining Wang, Liming Yang, Tanja Davidsen, Mark S. Guyer, Bradley A. Ozenberger, Heidi J. Sofia, Julie Bergsten, John Eckman, Jodi Harr, Jerome Myers, Christine Smith, Kelly Tucker, Cindy Winemiller, Leigh Anne Zach, Julia Y. Ljubimova, Greg Eley, Brenda Ayala, Mark A. Jensen, Ari Kahn, Todd D. Pihl, David A. Pot, Yunhu Wan, Jennifer Eschbacher, Greg Foltz, Nathan Hansen, Parvi Hothi, Biaoyang Lin, Nameeta Shah, Jae-geun Yoon, Ching Lau, Michael Berens, Kristin Ardlie, Rameen Beroukhim, Scott L. Carter, Andrew D. Cherniack, Mike Noble, Juok Cho, Kristian Cibulskis, Daniel DiCara, Scott Frazer, Stacey B. Gabriel, Nils Gehlenborg, Jeff Gentry, David Heiman, Jaegil Kim, Rui Jing, Eric S. Lander, Michael Lawrence, Pei Lin, Will Mallard, Matthew Meyerson, Robert C. Onofrio, Gordon Saksena, Steve Schumacher, Carrie Sougnez, Petar Stojanov, Barbara Tabak, Doug Voet, Hailei Zhang, Lihua Zou, Gad Getz, Nathan N. Dees, Li Ding, Lucinda L. Fulton, Robert S. Fulton, Krishna-Latha Kanchi, Elaine R. Mardis, Richard K. Wilson, Stephen B. Baylin, David W. Andrews, Larry Harshyne, Mark L. Cohen, Karen Devine, Andrew E. Sloan, Scott R. VandenBerg, Mitchel S. Berger, Michael Prados, Daniel Carlin, Brian Craft, Kyle Ellrott, Mary Goldman, Theodore Goldstein, Mia Grifford, David Haussler, Singer Ma, Sam Ng, Sofie R. Salama, J. Zachary Sanborn, Joshua Stuart, Teresa Swatloski, Peter Waltman, Jing Zhu, Robin Foss, Barbara Frentzen, William Friedman, Raquel McTiernan, Anthony Yachnis, D. Neil Hayes, Charles M. Perou, Siyuan Zheng, Rahulsimham Vegesna, Yong Mao, Rehan Akbani, Kenneth Aldape, Oliver Bogler, Gregory N. Fuller, The Somatic Genomic Landscape of Glioblastoma Cell. ,vol. 155, pp. 462- 477 ,(2013) , 10.1016/J.CELL.2013.09.034
Chong Liu, Jonathan C. Sage, Michael R. Miller, Roel G.W. Verhaak, Simon Hippenmeyer, Hannes Vogel, Oded Foreman, Roderick T. Bronson, Akiko Nishiyama, Liqun Luo, Hui Zong, Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma Cell. ,vol. 146, pp. 209- 221 ,(2011) , 10.1016/J.CELL.2011.06.014
Sheila R. Alcantara Llaguno, Zilai Wang, Daochun Sun, Jian Chen, Jing Xu, Euiseok Kim, Kimmo J. Hatanpaa, Jack M. Raisanen, Dennis K. Burns, Jane E. Johnson, Luis F. Parada, Adult Lineage-Restricted CNS Progenitors Specify Distinct Glioblastoma Subtypes Cancer Cell. ,vol. 28, pp. 429- 440 ,(2015) , 10.1016/J.CCELL.2015.09.007