Combined oral administration of L-arginine and tetrahydrobiopterin in a rat model of pulmonary arterial hypertension

作者: C. Schreiber , M.S. Eilenberg , A. Panzenboeck , M.P. Winter , H. Bergmeister

DOI: 10.1086/689289

关键词: PharmacologyOral administrationArginineCombination therapyRat modelAnimal modelTetrahydrobiopterinMedicineNitric oxide

摘要: Alterations in the nitric oxide (NO) pathway play a major role pulmonary arterial hypertension (PAH). L-arginine (LA) and tetrahydrobiopterin (BH4) are main substrates production of NO, w...

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