作者: C. Schreiber , M.S. Eilenberg , A. Panzenboeck , M.P. Winter , H. Bergmeister
DOI: 10.1086/689289
关键词: Pharmacology 、 Oral administration 、 Arginine 、 Combination therapy 、 Rat model 、 Animal model 、 Tetrahydrobiopterin 、 Medicine 、 Nitric oxide
摘要: Alterations in the nitric oxide (NO) pathway play a major role pulmonary arterial hypertension (PAH). L-arginine (LA) and tetrahydrobiopterin (BH4) are main substrates production of NO, w...