Combination approaches to combat multidrug-resistant bacteria

作者: Roberta J. Worthington , Christian Melander

DOI: 10.1016/J.TIBTECH.2012.12.006

关键词: BioinformaticsAntibioticsDrug resistanceAntimicrobialMultidrug resistant bacteriaPharmacotherapyGlobal healthBiologyAntibiotic resistanceMicrobiologyBacteria

摘要: … Figure 1e) is an example of a non-β-lactam β-lactamase inhibitor, and has been shown to restore cephalosporin susceptibility to a large number of ESBL-producing Escherichia coli and …

参考文章(62)
Elie Dolgin, Sequencing of superbugs seen as key to combating their spread Nature Medicine. ,vol. 16, pp. 1054- 1054 ,(2010) , 10.1038/NM1010-1054A
D. Mitchison, G. Davies, The chemotherapy of tuberculosis: past, present and future. International Journal of Tuberculosis and Lung Disease. ,vol. 16, pp. 724- 732 ,(2012) , 10.5588/IJTLD.12.0083
Mette Bonde, Dorte H. Højland, Hans Jørn Kolmos, Birgitte H. Kallipolitis, Janne K. Klitgaard, Thioridazine affects transcription of genes involved in cell wall biosynthesis in methicillin-resistant Staphylococcus aureus. Fems Microbiology Letters. ,vol. 318, pp. 168- 176 ,(2011) , 10.1111/J.1574-6968.2011.02255.X
N. Petrosillo, E. Ioannidou, M.E. Falagas, Colistin monotherapy vs. combination therapy: evidence from microbiological, animal and clinical studies Clinical Microbiology and Infection. ,vol. 14, pp. 816- 827 ,(2008) , 10.1111/J.1469-0691.2008.02061.X
Christopher Walsh, Molecular mechanisms that confer antibacterial drug resistance Nature. ,vol. 406, pp. 775- 781 ,(2000) , 10.1038/35021219
S. Lee, A. Hinz, E. Bauerle, A. Angermeyer, K. Juhaszova, Y. Kaneko, P. K. Singh, C. Manoil, Targeting a bacterial stress response to enhance antibiotic action Proceedings of the National Academy of Sciences of the United States of America. ,vol. 106, pp. 14570- 14575 ,(2009) , 10.1073/PNAS.0903619106
Linda Ejim, Maya A Farha, Shannon B Falconer, Jan Wildenhain, Brian K Coombes, Mike Tyers, Eric D Brown, Gerard D Wright, None, Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy Nature Chemical Biology. ,vol. 7, pp. 348- 350 ,(2011) , 10.1038/NCHEMBIO.559
Leonard Amaral, Martin J. Boeree, Stephen H. Gillespie, Zarir F. Udwadia, Dick van Soolingen, Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now! International Journal of Antimicrobial Agents. ,vol. 35, pp. 524- 526 ,(2010) , 10.1016/J.IJANTIMICAG.2009.12.019
David Lane, Designer combination therapy for cancer. Nature Biotechnology. ,vol. 24, pp. 163- 164 ,(2006) , 10.1038/NBT0206-163