ANTIEMETIC EFFICACY OF PROPHYLACTIC ONDANSETRON IN LAPAROSCOPIC SURGERY: RANDOMIZED, DOUBLE-BLIND COMPARISON WITH METOCLOPRAMIDE

作者: J.H. RAPHAEL , A.C. NORTON

DOI: 10.1093/BJA/71.6.845

关键词: AnesthesiaMetoclopramideAntiemetic AgentOndansetronSurgeryPostoperative nausea and vomitingNauseaMedicineGeneral anaesthesiaVomitingAntiemetic

摘要: In a randomized, double-blind study, we have compared the prophylactic antiemetic efficacy of ondansetron with that metoclopramide in 123 patients undergoing general anaesthesia for day-case gynaecological laparoscopic surgery. The received either i.v. 4 mg or 10 immediately before standard anaesthetic. number no nausea vomiting ondansteron group was 50 (82%) 29 (47%) (P < 0.001). those previous history postoperative and vomiting, less severe receiving 0.05). We conclude preoperative administration superior to preventing after

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