Clinical Implications of Oscillatory Lung Function during Methacholine Bronchoprovocation Testing of Preschool Children
作者： Sun Hee Choi , Youn Ho Sheen , Mi Ae Kim , Ji Hyeon Baek , Hey Sung Baek
DOI: 10.1155/2017/9460190
关键词: Bronchodilator 、 Methacholine 、 Repeatability 、 Respiratory distress 、 Cardiology 、 Bronchial hyperresponsiveness 、 Airway obstruction 、 Lung function 、 Asthma 、 Medicine 、 Internal medicine 、 Pediatrics
摘要: Objective. To investigate the repeatability and safety of measuring impulse oscillation system (IOS) parameters point wheezing during bronchoprovocation testing preschool children. Methods. Two sets methacholine challenge were conducted in 36 asthma The test was discontinued if there a significant change reactance (Xrs5) resistance (Rrs5) at 5 Hz (Condition 1) or respiratory distress due to airway obstruction 2). PC80_Xrs5, PC30_Rrs5, (PCw) assessed. changes -scores SD-indexes from prebaseline (before testing) postbaseline (after bronchodilator) determined. Results. For PCw for subjects, PC80_Xrs5 showed highest repeatability. Fifteen 70 tests met Condition . pre- values varied significantly Rrs5 Xrs5. Excluding subjects with higher than 2SD, we able detect 97.1% bronchial hyperresponsiveness based on A IOS associated all frequencies. Conclusion. Xrs5 have comparable FEV1, is more reliable Rrs5. Clinicians can safely perform by Rrs5, Xrs5, values.
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