Non-functioning parathyroid cystic tumour: malignant or not? Report of a case.

摘要: Parathyroid carcinoma (PC) is a very rare endocrine tumour, usually characterized by symptoms such as neck mass, dysphonia, severe hypercalcemia exceeding 140 mg/L and elevated serum parathyroid hormone levels, even more than 5 times the upper limit of normal. Non-functioning cancer extremely and, in this case, its pre-operative diagnosis often difficult. A 54-year old female patient, referring dysphagia underwent ultrasound CT. left thyroid nodule, probably cystic, was found. It presented caudal extent on anterior mediastinum causing compression lateral wall trachea. The preoperative calcemia into normal range. patient lobectomy. Histological exam showed cystic lesion, immunohistochemically originating from that oriented for carcinoma. 18 months follow-up did not show residual-recurrent disease. origin lesion could be suspected before surgery when specific laboratory tests are available clinical effects hyperparathyroidism syndrome present. features always sufficient differential between adenoma immunohistochemistry an useful tool can aid to reach definite diagnosis.