摘要: Parathyroid carcinoma is an uncommon cause of PTHdependent hypercalcemia. The collective published experience with this rare neoplasm has provided a distinctive clinical profile that differs in number respects from benign primary hyperparathyroidism (1–3). distinguishing features parathyroid assume even greater prominence when viewed within the current context hyperparathyroidism, which commonly presents today as mild asymptomatic disease (4–8). In report, features, natural history and prognosis cancer are reviewed. Surgical approaches to outlined well medical therapies hypercalcemia accompanies recurrent or metastatic disease. As ultimate depends major extent upon successful resection tumor at time initial operation, emphasis placed those help differentiate it due adenomatous hyperplastic