Multiglandular parathyroid carcinoma: a case report and brief review.

作者: Prem Sahasranam , Michael T. Tran , Hezla Mohamed , Theodore C. Friedman

DOI: 10.1097/SMJ.0B013E318073CA37

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摘要: A 53-year-old man with no past medical history was admitted complaints of hematuria, flank and abdominal pain one week duration. He also complained an enlarging new neck mass month before presentation. The laboratory assessment showed a calcium level 17.3 mg/dL (normal 8.5-10.5 mg/dL), serum albumin 2.9 g/dL 3.0-5.0 g/dL), creatinine 3.4 0.5-1.2 mg/dL). ultrasound complicated left mass. hydrated for improvement in his labs, showing decrease to 9.3 1.8 mg/dL. underwent total thyroidectomy parathyroidectomy. pathology multiglandular parathyroid carcinoma. It is important the physician surgeon dealing primary hyperparathyroidism look better knowledge understanding this condition would aid early diagnosis possibly increase survival rate.

参考文章(31)
Elizabeth Shane, Clinical review 122: Parathyroid carcinoma. The Journal of Clinical Endocrinology and Metabolism. ,vol. 86, pp. 485- 493 ,(2001) , 10.1210/JCEM.86.2.7207
O H Clark, K E Levin, M Galante, Parathyroid carcinoma versus parathyroid adenoma in patients with profound hypercalcemia. Surgery. ,vol. 101, pp. 649- 660 ,(1987)
Stephen J. Marx, Hyperparathyroid and hypoparathyroid disorders. The New England Journal of Medicine. ,vol. 343, pp. 1863- 1875 ,(2000) , 10.1056/NEJM200012213432508
Mishaela R. Rubin, Shonni J. Silverberg, Editorial: HRPT2 in parathyroid cancer: a piece of the puzzle. The Journal of Clinical Endocrinology and Metabolism. ,vol. 90, pp. 5505- 5507 ,(2005) , 10.1210/JC.2005-1578
J F Smith, R R Coombs, Histological diagnosis of carcinoma of the parathyroid gland. Journal of Clinical Pathology. ,vol. 37, pp. 1370- 1378 ,(1984) , 10.1136/JCP.37.12.1370
Vincent L. Cryns, Ann Thor, Hong-Ji Xu, Shi-Xue Hu, Margaret E. Wierman, Austin L. Vickery, William F. Benedict, Andrew Arnold, Loss of the retinoblastoma tumor-suppressor gene in parathyroid carcinoma The New England Journal of Medicine. ,vol. 330, pp. 757- 761 ,(1994) , 10.1056/NEJM199403173301105
Takao Obara, Takahiro Okamoto, Masako Kanbe, Masatoshi Iihara, Functioning parathyroid carcinoma: Clinicopathologic features and rational treatment Seminars in Surgical Oncology. ,vol. 13, pp. 134- 141 ,(1997) , 10.1002/(SICI)1098-2388(199703/04)13:2<134::AID-SSU9>3.0.CO;2-A
Lori A. Erickson, Long Jin, Peter Wollan, Geoffrey B. Thompson, Jon A. van Heerden, Ricardo V. Lloyd, Parathyroid hyperplasia, adenomas, and carcinomas: differential expression of p27Kip1 protein. The American Journal of Surgical Pathology. ,vol. 23, pp. 288- 295 ,(1999) , 10.1097/00000478-199903000-00007
Takao Obara, Yoshihide Fujimoto, Akira Hirayama, Yoshiharu Kanaji, Yukio Ito, Takaya Kodama, Takesaburo Ogata, None, Flow cytometric dna analysis of parathyroid tumors with special reference to its diagnostic and prognostic value in parathyroid carcinoma Cancer. ,vol. 65, pp. 1789- 1793 ,(1990) , 10.1002/1097-0142(19900415)65:8<1789::AID-CNCR2820650820>3.0.CO;2-N
V L Cryns, M P Rubio, A D Thor, D N Louis, A Arnold, p53 abnormalities in human parathyroid carcinoma The Journal of Clinical Endocrinology and Metabolism. ,vol. 78, pp. 1320- 1324 ,(1994) , 10.1210/JCEM.78.6.8200932