Zinc content in discrete hippocampal and amygdaloid areas of the epilepsy (El) mouse and normal mice.
作者： Motofumi Fukahori , Masatoshi Itoh , Kiyoshi Oomagari , Hiroaki Kawasaki
DOI: 10.1016/0006-8993(88)90099-6
关键词: Zinc 、 Endocrinology 、 Dentate gyrus 、 Pathophysiology 、 Neuroscience 、 Convulsive Seizures 、 Hippocampus 、 Hippocampal formation 、 Epilepsy 、 Chemistry 、 Amygdala 、 Internal medicine
摘要: In the present study, zinc content was determined in discrete hippocampal and amygdaloid areas of 3 strains mice (El, ddY CBA) using an atomic absorption spectrophotometer. Zinc significantly lower dentate area El strain compared to CBA strains. The mouse is considered animal model for epilepsy seizures this appear originate hippocampus. results suggest possible involvement pathophysiology convulsive epileptic mouse.
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sci-hub.se 参考文章(25)
J. Donaldson, T. St. Pierre, J. L. Minnich, A. Barbeau, Determination of Na+, K+, Mg2+, Cu2+, Zn2+, and Mn2+ in Rat Brain Regions Canadian Journal of Biochemistry. ,vol. 51, pp. 87- 92 ,(1973) , 10.1139/O73-010
Patrick Lawrence Tuff, The Effects of Kindling on GABA-mediated Inhibition in the Dentate Gyrus of the Rat ,(1982)
F. Timm, Zur Histochemie des Ammonshorngebietes Zeitschrift f�r Zellforschung und Mikroskopische Anatomie. ,vol. 48, pp. 548- 555 ,(1958) , 10.1007/BF00342730
G. L. King, R. Dingledine, J. L. Giacchino, J. O. McNamara, Abnormal neuronal excitability in hippocampal slices from kindled rats Journal of Neurophysiology. ,vol. 54, pp. 1295- 1304 ,(1985) , 10.1152/JN.1985.54.5.1295
J. Wensink, W. J. M. Lenglet, R. D. Vis, C. J. A. Van den Hamer, The effect of dietary zinc deficiency on the mossy fiber zinc content of the rat hippocampus: a microbeam PIXE study Histochemistry and Cell Biology. ,vol. 87, pp. 65- 69 ,(1987) , 10.1007/BF00518726
James C. Wallwork, David B. Milne, Rodger L. Sims, Harold H. Sandstead, Severe Zinc Deficiency: Effects on the Distribution of Nine Elements (Potassium, Phosphorus, Sodium, Magnesium, Calcium, Iron, Zinc, Copper and Manganese) in Regions of the Rat Brain Journal of Nutrition. ,vol. 113, pp. 1895- 1905 ,(1983) , 10.1093/JN/113.10.1895
T. Sutula, C. Harrison, O. Steward, Chronic epileptogenesis induced by kindling of the entorhinal cortex: the role of the dentate gyrus. Brain Research. ,vol. 385, pp. 291- 299 ,(1986) , 10.1016/0006-8993(86)91075-9
I. L. CRAWFORD, J. D. CONNOR, Localization and Release of Glutamic Acid in Relation to the Hippocampal Mossy Fibre Pathway Nature. ,vol. 244, pp. 442- 443 ,(1973) , 10.1038/244442A0
Takahiro Kumamaru, James F. Riordan, Bert L. Vallee, Determination of picogram quantities of zinc in zinc metalloproteins by atomic absorption spectrometry using a graphite furnace atomizer Analytical Biochemistry. ,vol. 126, pp. 214- 221 ,(1982) , 10.1016/0003-2697(82)90132-4
A. Barbeau, J. Donaldson, Zinc, taurine, and epilepsy. JAMA Neurology. ,vol. 30, pp. 52- 58 ,(1974) , 10.1001/ARCHNEUR.1974.00490310054009