Gene expression patterns related to osteogenic differentiation of bone marrow-derived mesenchymal stem cells during ex vivo expansion.

作者: Donatella Granchi , Gorka Ochoa , Elisa Leonardi , Valentina Devescovi , Serena Rubina Baglìo

DOI: 10.1089/TEN.TEC.2009.0405

关键词: BiologyPathologyWnt signaling pathwayBone cellCell biologyStem cell transplantation for articular cartilage repairCellular differentiationGene expression profilingBone marrowBone regenerationMesenchymal stem cell

摘要: … expression pattern underlying the osteogenic differentiation of MSCs during ex vivo expansion… The transcription profile related to the osteogenic differentiation of MSCs was analyzed by …

参考文章(40)
I. Ogawa, Takashi Takata, Yasusei Kudo, H. Hatano, B.S.M.S. Siriwardena, Periostin : Novel diagnostic and therapeutic target for cancer Histology and Histopathology. ,vol. 22, pp. 1167- 1174 ,(2007) , 10.14670/HH-22.1167
Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe, Frank Speleman, Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes Genome Biology. ,vol. 3, pp. 1- 12 ,(2002) , 10.1186/GB-2002-3-7-RESEARCH0034
Conor J Hurson, Joseph S Butler, Dominic T Keating, David W Murray, Denise M Sadlier, John M O'Byrne, Peter P Doran, Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis. BMC Musculoskeletal Disorders. ,vol. 8, pp. 12- 12 ,(2007) , 10.1186/1471-2474-8-12
Genevieve M. Boland, Geraldine Perkins, David J. Hall, Rocky S. Tuan, Wnt 3a promotes proliferation and suppresses osteogenic differentiation of adult human mesenchymal stem cells Journal of Cellular Biochemistry. ,vol. 93, pp. 1210- 1230 ,(2004) , 10.1002/JCB.20284
Paul E. Di Cesare, Carrie Fang, Michael P. Leslie, Hermina Tulli, Roberto Perris, Cathy S. Carlson, Expression of cartilage oligomeric matrix protein (COMP) by embryonic and adult osteoblasts. Journal of Orthopaedic Research. ,vol. 18, pp. 713- 720 ,(2000) , 10.1002/JOR.1100180506
Gary Brooke, Matthew Cook, Chris Blair, Rachel Han, Celena Heazlewood, Ben Jones, Melinda Kambouris, Kate Kollar, Steven McTaggart, Rebecca Pelekanos, Alison Rice, Tony Rossetti, Kerry Atkinson, Therapeutic applications of mesenchymal stromal cells. Seminars in Cell & Developmental Biology. ,vol. 18, pp. 846- 858 ,(2007) , 10.1016/J.SEMCDB.2007.09.012
G. Ciapetti, L. Ambrosio, G. Marletta, N. Baldini, A. Giunti, Human bone marrow stromal cells: In vitro expansion and differentiation for bone engineering Biomaterials. ,vol. 27, pp. 6150- 6160 ,(2006) , 10.1016/J.BIOMATERIALS.2006.08.025
M. Dominici, K. Le Blanc, I. Mueller, I. Slaper-Cortenbach, F.C Marini, D.S. Krause, R.J. Deans, A. Keating, D.J. Prockop, E.M. Horwitz, Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement Cytotherapy. ,vol. 8, pp. 315- 317 ,(2006) , 10.1080/14653240600855905
V. ROSEN, BMP and BMP inhibitors in bone. Annals of the New York Academy of Sciences. ,vol. 1068, pp. 19- 25 ,(2006) , 10.1196/ANNALS.1346.005
Jonathan I. Dawson, Richard O.C. Oreffo, Bridging the regeneration gap: stem cells, biomaterials and clinical translation in bone tissue engineering. Archives of Biochemistry and Biophysics. ,vol. 473, pp. 124- 131 ,(2008) , 10.1016/J.ABB.2008.03.024