The Potential of Stem Cells as an In Vitro Source of Red Blood Cells for Transfusion
作者： Anna Rita Migliaccio , Carolyn Whitsett , Thalia Papayannopoulou , Michel Sadelain
DOI: 10.1016/J.STEM.2012.01.001
关键词: Immunology 、 Cell growth 、 Biology 、 In vitro 、 Stem cell 、 Erythrocyte transfusion 、 Cell biology 、 Cell 、 Translation (biology) 、 Cell culture
摘要: Recent advances have increased excitement about the potential for therapeutic production of red blood cells (RBCs) in vitro. However, generation RBCs in large numbers required transfusion remains a significant challenge. In this article, we summarize recent progress producing from various cell sources, and discuss hurdles that remain translation into clinical arena.
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