Glycyrrhizin reduces HMGB1 secretion in lipopolysaccharide-activated RAW 264.7 cells and endotoxemic mice by p38/Nrf2-dependent induction of HO-1
作者： Young Min Kim , Hye Jung Kim , Ki Churl Chang
DOI: 10.1016/J.INTIMP.2015.03.014
关键词: Molecular biology 、 Heme oxygenase 、 Transfection 、 Glycyrrhizin 、 RAW 264.7 Cells 、 Biochemistry 、 Lipopolysaccharide 、 p38 mitogen-activated protein kinases 、 Secretion 、 HMGB1 、 Biology
摘要: … We provide strong evidence that glycyrrhizin induces HO-1 via p38MAPK/Nrf2-dependent … We found that p38 MAPK plays an important role in the induction of HO-1 by glycyrrhizin. …
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