Combination of Irinotecan (CPT-11) plus 5-Fluorouracil and Leucovorin (FOLFIRI Regimen) as First Line Treatment for Elderly Patients with Metastatic Colorectal Cancer: A Phase II Trial

作者: J. Souglakos , A. Pallis , S. Kakolyris , D. Mavroudis , N. Androulakis

DOI: 10.1159/000089992

关键词: Bolus (medicine)IrinotecanOncologyColorectal cancerInternal medicineFluorouracilAntimetaboliteFOLFIRI RegimenFOLFIRISurgeryThymidylate synthaseMedicine

摘要: Purpose: To evaluate the efficacy and tolerance of irinotecan (CPT-11) in combination with bolus continuous infusion 5-fluorouracil (5-FU) leucovorin (LV) (FOLFIRI regime

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