Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
作者： Michelle G. Lihou , Yaw-Huei Hsiang , Leroy F. Liu
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摘要: … the presence of topoisomerase I. Addition of excess purified calf thymus DNA topoisomerase I to this extract system in the presence of … In the absence of exogenous topoisomerase I and …
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