Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro.

作者: L. Yang , M. S. Wold , J. J. Li , T. J. Kelly , L. F. Liu

DOI: 10.1073/PNAS.84.4.950

关键词: Control of chromosome duplicationDNA supercoilReplication factor CTopoisomeraseDNA replicationDNA polymerase IIDNA polymeraseMolecular biologyBiologyEukaryotic DNA replication

摘要: … Addition of purified HeLa DNA topoisomerase II to extracts immunologically … specific inhibitor of mammalian DNA topoisomerase II (16, 18) was added to the extract, the topoisomerase II …

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