Melanoma never says die.
作者： Nikolas K. Haass , Udo Schumacher
DOI: 10.1111/EXD.12400
关键词: Smac mimetics 、 Cancer research 、 Immunology 、 Drug resistance 、 Melanoma 、 Bh3 mimetic 、 Targeted therapy 、 Disease progression 、 Medicine
摘要: Drug resistance in melanoma is commonly attributed to ineffective apoptotic pathways. Targeting apoptosis regulators thus considered a promising approach sensitizing therapy. In the previous issue of Experimental Dermatology, Plotz and Eberle discuss role that plays progression drug utility apoptosis-inducing BH3-mimetics as targeted There are number compounds clinical development field seems close translating recent findings into benefits for patients with melanoma. Thus, this viewpoint timely achieves valuable summary current state therapy
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core.ac.uk参考文章(20)
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