The pathology of head and neck tumors: Spindle cell lesions (sarcomatoid carcinomas, nodular fasciitis, and fibrosarcoma) of the aerodigestive tracts, part 14

摘要: The term spindle cell lesion, or tumor, is a purely descriptive one and if applied without further qualification meaningless as guide to therapy prognosis. three lesions presented in this report--sarcomatoid carcinomas, nodular fasciitis, fibrosarcoma--serve illustrate point. One, the sarcomatoid carcinoma, an epithelial malignancy which majority of sarcoma-like cells are believed be variants cells. Nodular self-limited benign soft tissue composed principally myofibroblasts. Primarily extramucosal it presents pseudosarcomatous microscopic appearance. Fibrosarcomas represent other end lesion spectrum that they malignancies fibroblastic origin. Clinical, pathologic, biologic implications these when arise mucosae upper aerodigestive tracts head neck presented.