Inflammatory markers and Lp(a) levels as cardiovascular risk factors in androgenetic alopecia.

作者: Amparo Vayá , Ana Sarnago , José M. Ricart , Verónica López , M.L. Martínez-Triguero

DOI: 10.3233/CH-141913

关键词: Internal medicineLipoproteinFibrinogenFree androgen indexC-peptideEndocrinologyInsulin resistanceInsulinMetabolic syndromeGlobulinMedicine

摘要: It is not well-established whether patients with androgenetic alopecia (AGA) show a higher cardiovascular risk and prevalence of metabolic syndrome (MS). Therefore, we aimed to analyze the MS by means case-control study. We determined lipidic, inflammatory, hormonal insulin resistance parameters conventional laboratory methods in 50 male early-onset AGA controls. did statistical differences for (glucose, insulin, C peptide, HOMA), lipids (total-cholesterol, HDL-cholesterol, tryglicerides) or (testosterone, free androgen index, sex hormone-binding globulin) P > 0.05, respectively. No between groups were observed its components (P 0.05). showed levels fibrino- gen, C-reactive protein (CRP) lipoprotein(a) (Lp(a)) = 0.016, 0.019 0.032, respectively). In unadjusted logistic regression analyses, PCR >4 mg/L, fibrinogen >395 mg/dL Lp(a) >59 increased AGA, but adjusted only mg/L independently this (OR 5.83, 95% CI 1.33-25.59 0.020; OR 3.94 1.08-14.43 0.038). The present study indicates that do either MS. However, characterised an increase inflammatory levels.

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