Lipid profile in patients with androgenetic alopecia: a meta‐analysis

作者: M.W. Kim , I.S. Shin , H.S. Yoon , S. Cho , H.S. Park

DOI: 10.1111/JDV.14000

关键词:

摘要: Background Many studies have reported that androgenetic alopecia (AGA) might be a risk factor for cardiovascular disorders, and the association of AGA with dyslipidemia has been studied. However, results were controversial previous meta-analyses had several critical limitations. Objective We performed meta-analysis to clarify whether patients abnormal lipid profiles. Methods A literature search was using MEDLINE, EMBASE, The Cochrane Library, KOREA MED databases. Results We pooled 19 observational compare serum total cholesterol, triglyceride (TG), low-density lipoprotein (LDL) high-density (HDL) cholesterol levels between control groups. TG, LDL significantly higher in group than group, standardized mean differences 0.377 (95% confidence interval [CI]: 0.182–0.572, p<.001), 0.426 CI: 0.164–0.688, p = .001), 0.450 0.171–0.728, =.002), respectively. In addition, HDL level lower difference -0.248 -0.472 -0.023, .030). Conclusions AGA showed statistically significant profiles, this partly explain diseases. This article is protected by copyright. All rights reserved.

参考文章(54)
Amparo Vayá, Ana Sarnago, José M. Ricart, Verónica López, M.L. Martínez-Triguero, Begoña Laiz, Inflammatory markers and Lp(a) levels as cardiovascular risk factors in androgenetic alopecia. Clinical Hemorheology and Microcirculation. ,vol. 61, pp. 471- 477 ,(2016) , 10.3233/CH-141913
Päivi Hirsso, Mauri Laakso, Veikko Matilainen, Liisa Hiltunen, Ulla Rajala, Jari Jokelainen, Sirkka Keinänen-Kiukaanniemi, Association of insulin resistance linked diseases and hair loss in elderly men. Finnish population-based study. Central European Journal of Public Health. ,vol. 14, pp. 78- 81 ,(2006) , 10.21101/CEJPH.B0045
M Kayatas, F Acibucu, F Candan, The association of insulin resistance and metabolic syndrome in early androgenetic alopecia Singapore Medical Journal. ,vol. 51, pp. 931- 936 ,(2010)
Bruce Lobaugh, Barbara J. Mathias, David F. Paulson, Samuel M. Lesko, Cary N. Robertson, Wendy Demark‐Wahnefried, Tara Smith Strigo, Mark R. Conaway, Richard V. Clark, Serum androgens: associations with prostate cancer risk and hair patterning. Journal of Andrology. ,vol. 18, pp. 495- 500 ,(1997) , 10.1002/J.1939-4640.1997.TB01964.X
José Gerardo González-González, Leonardo G. Mancillas-Adame, Mercedes Fernández-Reyes, Minerva Gómez-Flores, Fernando Javier Lavalle-González, Jorge Ocampo-Candiani, Jesús Zacarías Villarreal-Pérez, Androgenetic alopecia and insulin resistance in young men Clinical Endocrinology. ,vol. 71, pp. 494- 499 ,(2009) , 10.1111/J.1365-2265.2008.03508.X
Nermeen S. A. Abdel Fattah, Yasser W. Darwish, Androgenetic alopecia and insulin resistance: are they truly associated? International Journal of Dermatology. ,vol. 50, pp. 417- 422 ,(2011) , 10.1111/J.1365-4632.2010.04677.X
Vincent Descamps, Emmanuel Mahé, François Maccari, Edouard Begon, Hugues Barthelemy, Ziad Reguiai, Nathalie Bénéton, Eric Estève, Guillaume Chaby, Mireille Ruer-Mulard, Henry-Georges Steiner, Domitille Thomas-Beaulieu, Martine Avenel-Audran, Catherine Goujon-Henry, Michele-Lea Sigal, Khaled Ezzedine, Alain Beauchet, Severe androgenetic alopecia as a proxy of metabolic syndrome in male psoriatic patients older than 59 years. European Journal of Dermatology. ,vol. 24, pp. 356- 360 ,(2014) , 10.1684/EJD.2014.2346
Vincent Descamps, Béatrice Crickx, Philippe Le Toumelin, Serge Ahouansou, Association of androgenetic alopecia and hypertension European Journal of Dermatology. ,vol. 17, pp. 220- 222 ,(2007) , 10.1684/EJD.2007.0152
Alfredo Rebora, Baldness and coronary artery disease: the dermatologic point of view of a controversial issue. Archives of Dermatology. ,vol. 137, pp. 943- 947 ,(2001)
Salvador Arias-Santiago, María Teresa Gutiérrez-Salmerón, Agustín Buendía-Eisman, María Sierra Girón-Prieto, Ramón Naranjo-Sintes, Sex hormone-binding globulin and risk of hyperglycemia in patients with androgenetic alopecia. Journal of The American Academy of Dermatology. ,vol. 65, pp. 48- 53 ,(2011) , 10.1016/J.JAAD.2010.05.002