A mechanism of suppression of TGF–β/SMAD signaling by NF-κB/RelA
作者： Erwin P. Böttinger , Alfredo Dominguez-Rosales , Gero von Gersdorff , Amer A. Beg , Dan Liang
DOI: 10.1101/GAD.14.2.187
关键词: Cancer research 、 Biology 、 Phosphorylation 、 Signal transduction 、 RELA 、 Transforming growth factor 、 SMAD 、 Proinflammatory cytokine 、 Tumor necrosis factor alpha 、 NF-κB
摘要: … between opposing pathways and the TGF-β/SMAD signaling pathway is mediated through NF-κB… suppresses TGF-β/SMAD signaling through its direct interaction with the RI upon TGF-β …
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