Inherited Thrombophilia and Recurrent Pregnancy Loss
作者： Alireza Parand , Jale Zolghadri , Mozhgan Nezam , Abdolreza Afrasiabi , Sezaneh Haghpanah
DOI: 10.5812/IRCMJ.13708
关键词: Thrombophilia 、 Protein C 、 Gastroenterology 、 Protein S deficiency 、 Pediatrics 、 Factor V Leiden 、 Recurrent miscarriage 、 Medicine 、 Prothrombin G20210A 、 Protein C deficiency 、 Factor V 、 Internal medicine 、 General Medicine
摘要: Background: Recurrent pregnancy loss (RPL) is a common health problem. The polymorphisms G20210A of prothrombin gene (FII G 20210A), and 1691A factor V (Factor Leiden, FVL) are the most extensively studied thrombophilic mutations in association to recurrent miscarriage. Objectives: To determine frequency FII FVL as well protein C S deficiency series patients with RPL compared control group. Patients Methods: study group included 90 randomly selected three or more consecutive miscarriages same partner 0.05). Frequency was also not significantly different between case groups (P=0.906), but higher than controls (P=0.03). Genotype pattern healthy individuals were regard either Prothrombin (P > Conclusions: We determined significant controls. But two Leiden G20210A), miscarriage women.
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